Suppliers of antibody-drug conjugate payloads, including cytotoxic peptides, linkers, and conjugation services for ADC development. Peptide-based ADC payloads include cytotoxic peptides such as auristatins (MMAE, MMAF) and maytansinoids (DM1, DM4), which are conjugated to monoclonal antibodies via cleavable or non-cleavable linkers. ADC development requires specialized conjugation chemistry capabilities including maleimide-thiol coupling, click chemistry (CuAAC, SPAAC), and enzymatic conjugation using transglutaminase or sortase. Payload-linker stability, drug-to-antibody ratio (DAR) optimization, and hydrophobic interaction chromatography for aggregate characterization represent key technical competencies for ADC-focused CDMOs. Showing 2 listed suppliers.
Our directory lists suppliers offering adc payloads services across North America regions. Supplier types include CDMO. Browse individual profiles below for detailed capability information, manufacturing standards, and quality documentation.
Directory listing last reviewed July 2026.