NAD+ (nicotinamide adenine dinucleotide) is a naturally occurring coenzyme central to cellular metabolism, energy production, DNA repair, and sirtuin activation pathways. Despite its widespread use in wellness and longevity research, NAD+ is a small molecule coenzyme rather than a peptide under FDA and EMA regulatory definitions. NAD+ levels decline with age, driving research interest in NAD+ precursor supplementation using nicotinamide riboside (NR), nicotinamide mononucleotide (NMN), and nicotinamide. NAD+ and its precursors are commonly supplied as lyophilized powders or pre-formulated injectable solutions for research into mitochondrial function, cellular senescence, and metabolic regulation. Researchers should verify that NAD+ products are manufactured under appropriate quality controls with HPLC purity and residual solvent documentation.
Directory listing last reviewed July 2026.